how long does it take for the patient receiving leronlimab
how long does it take for the patient receiving leronlimab to turn the cold tumor hot enough to take an ICI? and what is the level of PD-L1 units that the FDA requires in order to approve the use of an ICI?
on the merck website the keytruda data says a TPS ( tumor progression score ) of 1% is all that is needed to allow use of keytruda. which is literally 1% of detectable cancer cells are expressing PD-L1? thats seems low to me....how does 1% of cells ability to receive and be affected by a drug affect how the tumor can be reduced? if the other 99% or oblivious to keytruda, what the use?
so then the obvious question is - at what percentage of detectable cancer cells does leronlimab flip these cold cells to hot ... also 1%? is that it? this all seems extremely low to me, what am i missing
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