My understanding is the first 5 would be all 350, then the safety check, then after that half 350 and half 700. Maybe the second 5 were 700, then randomized 50-50.
So worst case scenario after 30 patients would be about 12 patients on 700, 18 on 350 dosages. Very possible that it would be 15 and 15.
Only info about this at clinicaltrials.gov says
Quote:Participants will be randomized 1:1 to each arm, where approximately 30 participants will receive 350 mg of leronlimab + trifluridine and tipiracil + bevacizumab and approximately 30 will receive 700 mg of leronlimab + trifluridine and tipiracil + bevacizumab.