Oncotelic Therapeutics (OTCQB: OTLC), in collaboration with the Brush and Key Foundation, announced the publication of a peer-reviewed research article in the International Journal of Molecular Sciences titled “Comparative Tumor Microenvironment Analysis for HCC and PDAC Using KMplotter,” which analyzes the prognostic significance of biomarkers DNMT3A and GMPS across hepatocellular carcinoma and pancreatic ductal adenocarcinoma. Drawing on survival, transcriptomic, and tumor microenvironment data from more than 7,000 patients, the study demonstrates that biomarker relevance is highly context-dependent, shaped by immune composition, metabolic reprogramming, and innate immune signaling pathways, while also highlighting the role of structured mentorship in advancing translational oncology research.
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