Quote:if PD-L1 is increased to the point that an ICI can then take over and do its work (in a timely fashion, of course, not after the study's end! Misiu has drummed that into all of us ), it proves LL's efficacy in cold-to-hot without which the ICI could not work...
Yes! ICIs are not even part of SOC for Colorectal cancer, because they do not work on cold tumors. So if PD=L1 is elevated, it's because Leron elevated it, and if an ICI works on metastatic CRC, then it's because Leron enabled it. Period.