I never read anything about an immune checkpoint inhibitor in any of their posts. They acknowledged using Leronlimab at the start. They spoke about a chemo treatment the used electrical stimulation to try and better target the cancer cells. I think the standard of chemotherapy, and radiation were used, mainly. Additionally, he was kept on pretty high dosage steroids, to combat inflammation. I speculate that what Leronlimab got past the Blood Brain Barrier (BBB) was further diminished by the immune suppressing steroids. I do believe that Leronlimab helped dampen the trauma of the treatment, judging by his quality of life, compared to other patients going through the same types of chemo, radiation, and immune suppression. I believe Leronlimab needs closer study north of the BBB. Moreover, I believe that the Oncologist team needs to be fully on board with the use of Leronlimab (meaning; that if it is used, it should be used with treatment(s) that compliment its mechanisms of action. I believe that , for Glioblastoma Wild Type treatment, further study is needed with Leronlimab.