Here is a refresher on the mechanism of action of
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Posted On: 07/02/2025 8:25:00 PM
Here is a refresher on the mechanism of action of leronlimab that turns cold tumors into hot ones, thereby making them eligible to be treated with a PD-1 inhibitor.
Tumor's PD-L1 Upregulation
Unmasking the Mechanism
Remember, this 2nd mechanism of action would best be utilized in combination with subsequent treatment by a PD-1 blocker.
Don't forget that leronlimab has its own Primary Stand Alone mechanism of action as well, which has nothing to do with the upregulation of PD-L1 on tumor's CTC cells.
Tumor's PD-L1 Upregulation
Unmasking the Mechanism
Remember, this 2nd mechanism of action would best be utilized in combination with subsequent treatment by a PD-1 blocker.
Don't forget that leronlimab has its own Primary Stand Alone mechanism of action as well, which has nothing to do with the upregulation of PD-L1 on tumor's CTC cells.
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