Brilacidin is the most effective anti - Fungal, Bacterial,Viral
Post# of 72445
(Total Views: 56)
Posted On: 06/04/2025 11:25:16 AM
Absolute Sledge Hammer on drug resistant bacteria and viruses.
Subject: Brilacidin broad spectrum Anti Viral / Anti Bacterial /Anti Fungal
Recent Examples:
Boston Outbreak Eastern Equine Encephalitis.
Four Massachusetts towns—Webster, Oxford, Sutton, and Douglas—have imposed a voluntary evening lock down following the confirmation of a human case of Eastern Equine Encephalitis (EEE) in Worcester County, marking the first such case since 2020
https://www.thegatewaypundit.com/2024/08/volu...bat-deadly
There is no treatment for EEE. In Massachusetts, about half of the people identified with EEE died from the infection. People who survive this disease will often be permanently disabled. Few people recover completely.
Yes there Is!
Brilacidin can and has been proven effective against these weaponized and 2024 research and test proves this fact !!!!
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10819233/
As a matter of fact the military has conducted test using Brilacidin for Eastern Equine Encephalitis Virus (EEEV)
www.ipharminc.com/press-release/2022/9/14/new-in-vitro-data-supporting-the-broad-spectrum-antiviral-activity-of-innovation-pharmaceuticals-brilacidin-presented-at-2022-military-health-system-research-symposium
“Brilacidin, a Host Defense Peptide Mimetic, is a Broad-Spectrum Countermeasure Strategy Against Acutely Infectious Viruses.” Poster Presentation. 2022 Military Health System Research Symposium.
www.ipharminc.com/s/MHSRS2022-Brilacidin-poster-fv.pdf
Across multiple cell lines and under different testing conditions, research showed Brilacidin inhibited viral replication in a statistically significant manner in encephalitic alphaviruses, including Venezuelan Equine Encephalitis Virus (VEEV), Eastern Equine Encephalitis Virus (EEEV), and Sindbis Virus (SINV). Brilacidin also was shown to inhibit Rift Valley Fever Virus (RVRF), a contagious bunyavirus that can lead to blindness, liver failure, and hemorrhagic fever in infected individuals. Moreover, anti-inflammatory activity was observed, indicating intracellular events are modulated by Brilacidin treatment. Brilacidin is thus able to exert a combined protective effect by decreasing viral and inflammatory load.
The data Sheet
https://www.medchemexpress.com/Brilacidin.html
This link also includes:
MIC (MIC - Minimum Inhibitory Concentration - MIC90 - means 90% of isolates were inhibited in the 8 and 4 ug/mL range)
Brilacidin (PMX 30063) is an anti-infective antimicrobial with MIC90s of 1 and 8 μg/mL for Gram-positive bacteria Streptococcus pneumonia and Streptococcus viridans, and MIC90 of 8 and 4 μg/mL for Gram-negative bacteria Haemophilus influenza and Pseudomonas aeruginosa. Brilacidin is a defensin mimetic antibiotic compound.
Fact: It has stopped 11 strains of weaponized anthrax and countless other weaponized pathogens.
At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Brilacidin tetrahydrochloride) usually boasts enhanced water solubility and stability.
From the SDS ( Safety Data Sheet)
2. HAZARDS IDENTIFICATION: One of the highest safety ratings of any drug
2.1 Classification of the substance or mixture
Not a hazardous substance or mixture.
2.2 GHS Label elements, including precautionary statements
Not a hazardous substance or mixture.
2.3 Other hazards
None.
Subject: Brilacidin broad spectrum Anti Viral / Anti Bacterial /Anti Fungal
Recent Examples:
Boston Outbreak Eastern Equine Encephalitis.
Four Massachusetts towns—Webster, Oxford, Sutton, and Douglas—have imposed a voluntary evening lock down following the confirmation of a human case of Eastern Equine Encephalitis (EEE) in Worcester County, marking the first such case since 2020
https://www.thegatewaypundit.com/2024/08/volu...bat-deadly
There is no treatment for EEE. In Massachusetts, about half of the people identified with EEE died from the infection. People who survive this disease will often be permanently disabled. Few people recover completely.
Yes there Is!
Brilacidin can and has been proven effective against these weaponized and 2024 research and test proves this fact !!!!
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10819233/
As a matter of fact the military has conducted test using Brilacidin for Eastern Equine Encephalitis Virus (EEEV)
www.ipharminc.com/press-release/2022/9/14/new-in-vitro-data-supporting-the-broad-spectrum-antiviral-activity-of-innovation-pharmaceuticals-brilacidin-presented-at-2022-military-health-system-research-symposium
“Brilacidin, a Host Defense Peptide Mimetic, is a Broad-Spectrum Countermeasure Strategy Against Acutely Infectious Viruses.” Poster Presentation. 2022 Military Health System Research Symposium.
www.ipharminc.com/s/MHSRS2022-Brilacidin-poster-fv.pdf
Across multiple cell lines and under different testing conditions, research showed Brilacidin inhibited viral replication in a statistically significant manner in encephalitic alphaviruses, including Venezuelan Equine Encephalitis Virus (VEEV), Eastern Equine Encephalitis Virus (EEEV), and Sindbis Virus (SINV). Brilacidin also was shown to inhibit Rift Valley Fever Virus (RVRF), a contagious bunyavirus that can lead to blindness, liver failure, and hemorrhagic fever in infected individuals. Moreover, anti-inflammatory activity was observed, indicating intracellular events are modulated by Brilacidin treatment. Brilacidin is thus able to exert a combined protective effect by decreasing viral and inflammatory load.
The data Sheet
https://www.medchemexpress.com/Brilacidin.html
This link also includes:
MIC (MIC - Minimum Inhibitory Concentration - MIC90 - means 90% of isolates were inhibited in the 8 and 4 ug/mL range)
Brilacidin (PMX 30063) is an anti-infective antimicrobial with MIC90s of 1 and 8 μg/mL for Gram-positive bacteria Streptococcus pneumonia and Streptococcus viridans, and MIC90 of 8 and 4 μg/mL for Gram-negative bacteria Haemophilus influenza and Pseudomonas aeruginosa. Brilacidin is a defensin mimetic antibiotic compound.
Fact: It has stopped 11 strains of weaponized anthrax and countless other weaponized pathogens.
At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Brilacidin tetrahydrochloride) usually boasts enhanced water solubility and stability.
From the SDS ( Safety Data Sheet)
2. HAZARDS IDENTIFICATION: One of the highest safety ratings of any drug
2.1 Classification of the substance or mixture
Not a hazardous substance or mixture.
2.2 GHS Label elements, including precautionary statements
Not a hazardous substance or mixture.
2.3 Other hazards
None.
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