Do we really need Bionano Genomics' OGM? Opti
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Posted On: 05/10/2025 6:42:51 AM
Do we really need Bionano Genomics' OGM?
Optical Genome Mapping (OGM) offers advantages over traditional methods like FISH, PCR, and CMA by detecting large structural variations with higher resolution. While these older techniques can identify specific genetic mutations, they often require multiple tests to get a full picture, whereas OGM consolidates genomic analysis into one streamlined workflow, improving accuracy in cancer and rare disease research.
Although transitioning to OGM involves an initial investment, it can save time and costs by reducing the need for multiple separate tests. Many leading institutions are integrating OGM with sequencing technologies to ensure both sequence-level and structural insights, making it a future-ready approach for comprehensive genomic analysis.
Optical Genome Mapping (OGM) offers advantages over traditional methods like FISH, PCR, and CMA by detecting large structural variations with higher resolution. While these older techniques can identify specific genetic mutations, they often require multiple tests to get a full picture, whereas OGM consolidates genomic analysis into one streamlined workflow, improving accuracy in cancer and rare disease research.
Although transitioning to OGM involves an initial investment, it can save time and costs by reducing the need for multiple separate tests. Many leading institutions are integrating OGM with sequencing technologies to ensure both sequence-level and structural insights, making it a future-ready approach for comprehensive genomic analysis.
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