Could it put an end to lymphedema? It may decr

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Could it put an end to lymphedema?

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It may decrease it. IL-2 and GM-CSF can tighten the junctures that release lymphatic fluid, lowering them (which leronlimab does) might increase lymphatic drainage.

A paper was released that showed lowering a protein called ROCK2 through reductions in cytokines can increase lymphatic drainage. ROCK2 is activated by the cAMP protein which is also downregulated by leronlimab.

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Mechanistically, we further observed a cytokine-induced shift in the expression of the ROCK2 isoform in LECs and identified a unique ROCK2/junctional adhesion molecule-A (JAM-A) complex that was responsible for the cytokine-induced lymphatic junction zippering. Knockdown of ROCK2 in the human LECs abrogated cytokine-induced drainage dysfunction, and lymphatic-specific knockout of ROCK2 reversed lymphedema in vivo.
https://www.pnas.org/doi/full/10.1073/pnas.2308941120

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Lymphedema may or may not be in my list of diseases to look at (that I may never get around too). I won't know until I actually get around to installing a power supply in my other computer.