CCR5 & bacteria: CCR5 is a receptor for Staphyl

CCR5 & bacteria:

CCR5 is a receptor for Staphylococcus aureus leukotoxin ED, and CCR5+ cells are targeted by the bacteria.

*Infections of the skin or other soft tissues by the hard-to-treat MRSA (methicillin-resistant Staphylococcus aureus) bacteria appear to permanently compromise the lymphatic system, which is crucial to immune system function. Jan 22, 2018

*LukED targets the chemokine receptor CCR5 to kill T lymphocytes, macrophages and dendritic cells.

Staphylococcus aureus (staph) can cause a wide range of infections, from minor skin problems like boils and impetigo, to more serious conditions like pneumonia, endocarditis, and septicemia.

Google:
* Endocarditis, or infective endocarditis (IE), is inflammation of the inner lining of the heart.

Structure and function of the lymphatic system:

https://www.gpoh.de/kinderkrebsinfo/content/d...x_eng.html

*The C-C chemokine receptor type 5 (CCR5) plays a role in microbial infections beyond HIV, influencing immune responses and susceptibility to certain pathogens, including West Nile virus, Zika virus, and Staphylococcus aureus.

Our NASH/MASH protocol mentions CCR5 for West Nile Virus.

*Antibiotics commonly prescribed to treat staph infections include cefazolin, nafcillin, oxacillin, vancomycin, daptomycin and linezolid. May 25, 2022