I've sorta resigned myself to never smelling anyth

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I've sorta resigned myself to never smelling anything again... But reprogramed stem cells? Had no idea. Wow... gotta look into that. Think it would work for anosmia?

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That would be from nerve damage. Now that they can repair them with stem cells it's possible but may be a little trickier in the brain rather than the spinal column.

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I know leronlimab has shown promise in stroke and TBIs. But its been two and a half years. Has the window of opportunity to provide some kind of therapeutic benefit come and gone? Ohm--any thoughts?

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The mechanism of action hasn't changed so it hasn't come and gone. In fact they're going to be doing a pre-clinical study in stroke.

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The only other lead I've come across is psychedelics! LSD and mushrooms. In an online journal as I recall, that looked at three case studies and worked out the theoretical basis. But I only had a look at the abstract as the paper was behind a paywall.

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I could see psychedelics enhancing the perceived sense of smell (although not the actual sense of smell) but it would do nothing for destroyed neurons.