Thank you brentie for the reminder of how wonderfu

Thank you brentie for the reminder of how wonderful our Leronlimab can be.

It would be nice to know if Patient #2 is cancer free. I suppose we may find out in May. If she is still alive.... what a show that will be.

Patient #2: Enrolled in single IND. Patient is MBC with HER2+ stage 4 metastasis to lung, liver, and brain. Patient’s radiologist cancelled 2nd round of treatment due to leronlimab’s effect on shrinking the largest tumor in the brain by 56% and other lesions being stable. Leronlimab has and continues to be the only treatment in place for brain metastasis after radiation was administered to this patient in July 2019. Four and one-half months after successful radiation treatment, the patient received her first dose of leronlimab (700 mg) and no other drugs to treat the brain metastasis. The 56% shrinkage in the brain lesions occurred after only two once-weekly injections of leronlimab. After 10 weeks of treatment with leronlimab, this patient’s CTC and EMT results were all zeros (results reported on 2/12/2020). The patient’s CT scan in mid-February was reported as stable.