I thought I remembered reading that we showed dece

Quote:

---

I thought I remembered reading that we showed decent results in GBM in our basket trial so I'm really curious why the mouse study didn't show positive results.

---

It may be something as simple as the mouse brain blood barrier is less leaky under inflammatory conditions and so less leronlimab gets through. Mice have a much more challenging environment when it comes to infective agents so it would make sense that their blood brain barrier would have to have tighter junctions under insult.