With very sick patients, they also don't want to b
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With very sick patients, they also don't want to be blamed by the public for excess deaths by an unproven drug (ie. making a bad problem like severe covid worse) so they probably capped at 2 saying we should see improvement by then if it works. All bad decisions in hindsight.
There was no need for hindsight. The MDs of the Safety Monitoring Committee could not but saw the fantastic improvements in the critical status of the LL cohort patients after 2 doses as well as their gradual worsening thereafter. At this point they were supposed to request to modify the trial by adding two more weeks of LL. Instead, they recommended to wait 42 days after the end of the trial before tabulating the result!?
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Le-Ron-Li-Mab, and they have not.