Investors Hangout Stock Message Boards Logo
  • Mailbox
  • Favorites
  • Boards
    • The Hangout
    • NASDAQ
    • NYSE
    • OTC Markets
    • All Boards
  • Whats Hot!
    • Recent Activity
    • Most Viewed Boards
    • Most Viewed Posts
    • Most Posted
    • Most Followed
    • Top Boards
    • Newest Boards
    • Newest Members
  • Blog
    • Recent Blog Posts
    • Recently Updated
    • News
    • Stocks
    • Crypto
    • Investing
    • Business
    • Markets
    • Economy
    • Real Estate
    • Personal Finance
  • Market Movers
  • Interactive Charts
  • Login - Join Now FREE!
  1. Home ›
  2. Stock Message Boards ›
  3. Stock Boards ›
  4. CytoDyn Inc (CYDY) Message Board

Someone asked me about Multiple Sclerosis and lero

Message Board Public Reply | Private Reply | Keep | Replies (2)                   Post New Msg
Edit Msg () | Previous | Next


Post# of 155128
(Total Views: 569)
Posted On: 10/29/2024 7:38:42 AM
Posted By: ohm20
Someone asked me about Multiple Sclerosis and leronlimab -

Multiple Sclerosis is an autoimmune disease where the myelin sheath covering the nerve fibers and the fibers themselves are damaged by heavily activated microglia and macrophages. That activation and movement to the myelin sheath is driven by the binding of ligands to CCR5 and other immune activation receptors upregulating inflammatory cytokines and increasing immune response. CCR5 is the CCR receptor with the highest expression and most responsible for an overactive immune response.

Leronlimab by blocking CCR5 downregulates a wide range of those inflammatory cytokines and would lower the overactive immune response seen in MS. Leronlimab's lack of serious adverse events in over 1,000 patients is also a plus.

Leronlimab Regulator List (a work in progress)
https://investorshangout.com/post/view?id=6700464

Shows results with leronlimab for some of the inflammatory proteins that it controls -

Leronlimab, mAb to CCR5, Trims Liver Fat in 14-Week Trial of NASH Patients
https://www.natap.org/2022/EASL/EASL_70.htm

CCR5 knockout suppresses experimental autoimmune encephalomyelitis in C57BL/6 mice
https://www.oncotarget.com/article/8097/text/

CCR5+ and CXCR3+ T cells are increased in multiple sclerosis and their ligands MIP-1α and IP-10 are expressed in demyelinating brain lesions
https://pmc.ncbi.nlm.nih.gov/articles/PMC22009/


(21)
(0)




CytoDyn Inc (CYDY) Stock Research Links


  1.  
  2.  


  3.  
  4.  
  5.  






Investors Hangout

Home

Mailbox

Message Boards

Favorites

Whats Hot

Blog

Settings

Privacy Policy

Terms and Conditions

Disclaimer

Contact Us

Whats Hot

Recent Activity

Most Viewed Boards

Most Viewed Posts

Most Posted Boards

Most Followed

Top Boards

Newest Boards

Newest Members

Investors Hangout Message Boards

Welcome To Investors Hangout

Stock Message Boards

American Stock Exchange (AMEX)

NASDAQ Stock Exchange (NASDAQ)

New York Stock Exchange (NYSE)

Penny Stocks - (OTC)

User Boards

The Hangout

Private

Global Markets

Australian Securities Exchange (ASX)

Euronext Amsterdam (AMS)

Euronext Brussels (BRU)

Euronext Lisbon (LIS)

Euronext Paris (PAR)

Foreign Exchange (FOREX)

Hong Kong Stock Exchange (HKEX)

London Stock Exchange (LSE)

Milan Stock Exchange (MLSE)

New Zealand Exchange (NZX)

Singapore Stock Exchange (SGX)

Toronto Stock Exchange (TSX)

Contact Investors Hangout

Email Us

Follow Investors Hangout

Twitter

YouTube

Facebook

Market Data powered by QuoteMedia. Copyright © 2025. Data delayed 15 minutes unless otherwise indicated (view delay times for all exchanges).
Analyst Ratings & Earnings by Zacks. RT=Real-Time, EOD=End of Day, PD=Previous Day. Terms of Use.

© 2025 Copyright Investors Hangout, LLC All Rights Reserved.

Privacy Policy |Do Not Sell My Information | Terms & Conditions | Disclaimer | Help | Contact Us