He was sensing his left side of his body recover
He was sensing his left side of his body recover again.
Motor learning, like when you're learning how to swing a bat to hit a ball, that type of learning is spontaneously re-activated following a stroke, but it takes years to achieve that.
Leronlimab would expedite that thousands of fold.
It's almost as if the neurons that fire when they need to to actuate the arms and legs need to relearn when they need to fire. The synchronous nature of muscle memory is imbedded into the neurons and if those neurons are injured by the stroke, then the arms and legs can't move.
CCR5 is upregulated in the stroke and impedes neuron recovery. Initially it is upregulated to protect the neuron, limiting the progression of damage from excessive stimulation, because excessive excitability following a stroke can kill a neuron, but after a few days, the neuron should be stimulated so it can heal, but the presence and persistence of the unblocked CCR5 impedes neuron healing and limits recovery.
When CCR5 is blocked by LL say a week after stroke, the recovery of neurons is greatly enhanced. You Really Enhance Stroke Recovery. That is why he felt his leg waking up, because the neurons were firing from his brain, through the spinal cord and into the sciatic nerve, causing quadriceps muscle contractions.
The electrical nervous signal needs to reach the extremities but it was blocked in the brain, but leronlimab enhanced recovery of those neurons and those signals needed to be resynchronized.
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