Another interesting note is that LL blocks CCR5 on
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Posted On: 10/15/2024 12:19:44 AM
Another interesting note is that LL blocks CCR5 on T-cells (Specialized white blood cells ) For that is where they bind, enter the cell, and begin the process of replication Leading to the ultimate destruction of that T cell, where those new virions can go out to find other T cells to infect.
It is thought that the majority of HIV reservoirs live in the gut, but there are other places like brain tissue where it is thought HIV lies dormant.
In order to replicate HIV needs a T-cell So by having 100% RO On those T cells, the ART’s and possibly the bnabs Can do their work getting inside the cells (Which is not something LL can do) And possibly killing floating virions, but those floating virions might actually end up dying or being captured by the immune system as they search for open CCR5 receptors - Which doesn’t exist because you have 100% RO from LL.
This is what we have been searching for for a very long time in HIV research and it appears we may have found a cure. The great news is that this is in addition to long acting LL and AAV.
Very optimistic news.
It is thought that the majority of HIV reservoirs live in the gut, but there are other places like brain tissue where it is thought HIV lies dormant.
In order to replicate HIV needs a T-cell So by having 100% RO On those T cells, the ART’s and possibly the bnabs Can do their work getting inside the cells (Which is not something LL can do) And possibly killing floating virions, but those floating virions might actually end up dying or being captured by the immune system as they search for open CCR5 receptors - Which doesn’t exist because you have 100% RO from LL.
This is what we have been searching for for a very long time in HIV research and it appears we may have found a cure. The great news is that this is in addition to long acting LL and AAV.
Very optimistic news.
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