Rukobia (fostemsavir) is a prescription medication used to treat HIV-1 infection in adults with multidrug-resistant HIV-1. It's taken orally in combination with other HIV medicines when standard combinations aren't effective:
How it works
Rukobia attaches to a protein on the HIV-1 virus, preventing it from interacting with T cells and reproducing. This slows the spread of infection.
When it's used
Rukobia is used when other antiretrovirals (ARVs) aren't effective due to resistance, intolerance, or safety concerns.
How it's taken
Rukobia is taken orally as a prolonged-release tablet, with a dose of 600 mg twice daily.
Side effects
Serious side effects include unexplained weight loss, severe tiredness, muscle aches, severe headaches, joint pain, numbness or tingling, vision changes, and signs of infection. Other side effects include heart rhythm problems and changes in liver function.
Immune Reconstitution Syndrome, which can include autoimmune disorders
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https://medicine.yale.edu/news/yale-medicine-...ainst-hiv/
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Although being a pill combo after all failed antiretrovirals, hats off to Dr. Lataillade for having designed a 1st @ BSM & leading a multi-country trial, to FDA approval.
Rukobia just does not perform even close to LL's level.
Of course the safety comparisons are also just a world of differences.
Two days ago Cytodyn said looking to possibly end needing antiretroviral. My guess is today is for pulling LL HIV into either ViiV or one of the other 2 BP's.
Rights to all Cytodyn's, LL-HIV based projects.
Including a re-filing of BLA.
This time also done right @ multiple countries.
Multiple forms of milestone payments to Cytodyn, later replaced with royalties from all HIV product lines.
Shall see.....
How it works
Rukobia attaches to a protein on the HIV-1 virus, preventing it from interacting with T cells and reproducing. This slows the spread of infection.
When it's used
Rukobia is used when other antiretrovirals (ARVs) aren't effective due to resistance, intolerance, or safety concerns.
How it's taken
Rukobia is taken orally as a prolonged-release tablet, with a dose of 600 mg twice daily.
Side effects
Serious side effects include unexplained weight loss, severe tiredness, muscle aches, severe headaches, joint pain, numbness or tingling, vision changes, and signs of infection. Other side effects include heart rhythm problems and changes in liver function.
Immune Reconstitution Syndrome, which can include autoimmune disorders
____
https://medicine.yale.edu/news/yale-medicine-...ainst-hiv/
____
Although being a pill combo after all failed antiretrovirals, hats off to Dr. Lataillade for having designed a 1st @ BSM & leading a multi-country trial, to FDA approval.
Rukobia just does not perform even close to LL's level.
Of course the safety comparisons are also just a world of differences.
Two days ago Cytodyn said looking to possibly end needing antiretroviral. My guess is today is for pulling LL HIV into either ViiV or one of the other 2 BP's.
Rights to all Cytodyn's, LL-HIV based projects.
Including a re-filing of BLA.
This time also done right @ multiple countries.
Multiple forms of milestone payments to Cytodyn, later replaced with royalties from all HIV product lines.
Shall see.....
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