NetworkNewsBreaks – Tonix Pharmaceuticals Holdin
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Tonix Pharmaceuticals Holding (NASDAQ: TNXP) is a biopharmaceutical company with marketed products and a pipeline of development candidates. Tonix’s TNX-801, a live-virus vaccine candidate, could potentially offer a more viable solution to address the growing global mpox crisis. TNX-801 shows promise because it appears to align with the preferred target product profile (“TPP”) recently issued by the World Health Organization (“WHO”). The TPP emphasizes a well-tolerated, single-dose vaccine that can be administered, shipped and stored in Africa and around the world.
Jynneos(R) and ACAM2000(R), two FDA-approved vaccines for mpox, do not fully meet WHO’s TPP. Thus, TNX-801 potentially offers a much-needed alternative. Preclinical trials of the vaccine candidate showed that it provides single-dose protection against the newly spreading strain of the monkeypox virus called Clade I. Additionally, TNX-801 is suitable for making lyophilized versions that are expected to be stable at ambient temperatures for about 8 hours, helping with logistics in various parts of the world. “Beyond its alignment with WHO’s single-dose requirement, TNX-801 seems to offer multiple competitive features that could position it as a viable contender in the global fight against mpox,” the press release reads.
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