From the Safety Data Sheet posted earlier So w
Post# of 72439
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Posted On: 07/28/2024 2:05:37 PM
From the Safety Data Sheet posted earlier
So what does it really cost to use Bril ?
Dosing uses 65ml per Kg in females and 75ml per Kg for males as a general guide line.
Taking 8ug/ml in upper dosing in their example and using a 100kg male 75ml * 100Kg = 7500ml
7500ml * 8ug = .06 or 60mg
This is intended as general reference for understanding the amount usedand it's attendant cost. I used the SDS article and is not intended in any shape form or format to be used as a clinical reference.
I am after a general reference of the cost per patient per dose.
Using 60 mg for a 100kg male and the cost per 10 mg of Brilacidin is $980 US therefore 6 X $980 =$5880 dollars. Obviously, if you wanted to sponsor a test and needed kg of the material the cost would come down dramatically around 99%.
If you had a disease or knew of a person that had a disease that there was no cure for most of us would throw $10,000 on the table in a heartbeat to help a fellow human being.
I just wanted to know what the bottom line cost was as I had never calculated it.
In many lab test with test cells containing a viral growth medium they were using concentrations on the order of 50~100ug / ml.
Where Brilacidin excels is it's ability as a defensin protein as it will strip the outer membrane in bacteria and Alpha viruses, thus leaving bacteria or viruses extremely vulnerable to the immune system and in many cases leaving the pathogen unable to obtain entry to the host cell. Believe it or not many of the foods we eat everyday will dock to the main protease in most viruses. Once the outer protective layer is removed from viruses and bacteria common foods we eat everyday contain organic molecules that will dock to the main protease in the virus, thus inhibiting the virus.
The immune system will easily disassemble the virus or bacteria at this point and create antibodies.
Cheers
So what does it really cost to use Bril ?
Dosing uses 65ml per Kg in females and 75ml per Kg for males as a general guide line.
Taking 8ug/ml in upper dosing in their example and using a 100kg male 75ml * 100Kg = 7500ml
7500ml * 8ug = .06 or 60mg
This is intended as general reference for understanding the amount usedand it's attendant cost. I used the SDS article and is not intended in any shape form or format to be used as a clinical reference.
I am after a general reference of the cost per patient per dose.
Using 60 mg for a 100kg male and the cost per 10 mg of Brilacidin is $980 US therefore 6 X $980 =$5880 dollars. Obviously, if you wanted to sponsor a test and needed kg of the material the cost would come down dramatically around 99%.
If you had a disease or knew of a person that had a disease that there was no cure for most of us would throw $10,000 on the table in a heartbeat to help a fellow human being.
I just wanted to know what the bottom line cost was as I had never calculated it.
In many lab test with test cells containing a viral growth medium they were using concentrations on the order of 50~100ug / ml.
Where Brilacidin excels is it's ability as a defensin protein as it will strip the outer membrane in bacteria and Alpha viruses, thus leaving bacteria or viruses extremely vulnerable to the immune system and in many cases leaving the pathogen unable to obtain entry to the host cell. Believe it or not many of the foods we eat everyday will dock to the main protease in most viruses. Once the outer protective layer is removed from viruses and bacteria common foods we eat everyday contain organic molecules that will dock to the main protease in the virus, thus inhibiting the virus.
The immune system will easily disassemble the virus or bacteria at this point and create antibodies.
Cheers
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