So, in the experiment, they took 4 monkeys infecte
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Posted On: 07/23/2024 11:32:05 PM
So, in the experiment, they took 4 monkeys infected with SHIV and infected them with the AAV that delivered the leronlimab gene.
Within 40 weeks, 2 of these monkeys had their viral loads down to zero.
With the other 2 monkeys, they developed antibodies against leronlimab which caused leronlimab to stop working. However, one of these 2 monkeys started to make leronlimab again and that same monkey is keeping viral load SHIV levels undetectable.
How to stop the development of antibodies against leronlimab?
What caused that one monkey to resume making leronlimab after all the antibodies against leronlimab were depleted and once leronlimab was being made again, why did those antibodies not return?
Within 40 weeks, 2 of these monkeys had their viral loads down to zero.
With the other 2 monkeys, they developed antibodies against leronlimab which caused leronlimab to stop working. However, one of these 2 monkeys started to make leronlimab again and that same monkey is keeping viral load SHIV levels undetectable.
How to stop the development of antibodies against leronlimab?
What caused that one monkey to resume making leronlimab after all the antibodies against leronlimab were depleted and once leronlimab was being made again, why did those antibodies not return?
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