Lupus an auto immune disease story. LL role? ht
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Posted On: 07/14/2024 7:21:10 AM
Lupus an auto immune disease story. LL role?
https://www.washingtonpost.com/wellness/2024/...-research/
Lupus is a complex autoimmune disease in which the immune system turns on the body, producing antibodies that attack the skin, joints, kidneys, brain or other organs.
In the study, the researchers compared the blood samples of people with lupus to a control group to measure the amount of certain white blood cells, T cells. Participants with lupus had higher levels of a specific T cell associated with the production of antibodies that can attack the body.
The researchers worked backward, following the chain of events in the immune system and i dentified insufficient activity of a receptor in the T cells, a protein called aryl hydrocarbon, as a potential root cause of the disease.
Now, they’re studying whether a novel therapy could activate that receptor, leading the T cells to behave differently and, ultimately, through a cascade of events in the immune system, treat the autoimmune disease.
https://www.washingtonpost.com/wellness/2024/...-research/
Lupus is a complex autoimmune disease in which the immune system turns on the body, producing antibodies that attack the skin, joints, kidneys, brain or other organs.
In the study, the researchers compared the blood samples of people with lupus to a control group to measure the amount of certain white blood cells, T cells. Participants with lupus had higher levels of a specific T cell associated with the production of antibodies that can attack the body.
The researchers worked backward, following the chain of events in the immune system and i dentified insufficient activity of a receptor in the T cells, a protein called aryl hydrocarbon, as a potential root cause of the disease.
Now, they’re studying whether a novel therapy could activate that receptor, leading the T cells to behave differently and, ultimately, through a cascade of events in the immune system, treat the autoimmune disease.
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