“how can the medical/pharma community remain so

“how can the medical/pharma community remain so oblivious (obvious to me) to the science…”

At some point the light bulb goes off and it is appreciated and endorsed in retrospect. The publications coming will cast more light on the evidence.

Copernican heliocentrism was heretical until the Ptolemaic view was cast aside. I am reminded also of the quest in search of the prize offered by the British Parliament for a serviceable means to calculate longitude to save the British ships from being wrecked. Literally the entire scientific community advocated documenting the position of planetary bodies, getting a sight and going to the tables…it took 16 years of observations to get those tables and while a solution it was inconvenient in the extreme. Today we take GPS for granted! John Harrison had a different approach and believed the problem could be solved with a time-piece that was accurate enough for the job. Harrison was a carpenter with no initial experience with clocks or time pieces. It took years of effort and a lot of convincing against the prejudices of the day but Harrison ultimately secured the prize. Harrison is the one who invented jeweled movement to solve the problem of friction that worked against accuracy. For more read Dava Sobel’s brilliantly written book Longitude. I saw Harrison’s time-pieces in the Maritime Museum in London and got emotional looking at them. Against all odds, a testament to the power of persistence when you know you are right.

The wait is awful but the arc of appreciation for the underlying dynamic that drives the inflammatory process that OHM and others here appreciate bends towards the truth. The naval disaster that triggered the prize Harrison sought (worth about $4 million today) involved the loss of nearly 2,000 sailors. When Leronlimab is pressed into service many more will be saved from cancer, MASH and (cue the OHM20 list here).