NetworkNewsBreaks – Genprex Inc. (NASDAQ: GNPX)
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Genprex (NASDAQ: GNPX), a clinical-stage gene therapy company focused on developing life-changing therapies for patients with cancer and diabetes, is expanding its nonclinical programs into new indications. According to the announcement, the company is expanding through sponsored research agreements and material transfer agreements with several academic research collaborators. The programs will be focused on studying TUSC2, the tumor suppressor gene used in Genprex’s lead drug candidate, REQORSA(R) (quaratusugene ozeplasmid), and NPRL2, another tumor suppressor gene. The company noted that new indications being evaluated include ALK-positive lung cancer as well as additional undisclosed programs. The expanded programs comprise research being conducted at the University of Michigan Rogel Cancer Center; Meharry Medical College in Nashville; and a major cancer research center in Houston. “We are developing a robust research program to expand the potential tumor targets, and even nontumor targets, that we may include in future clinical trials for REQORSA,” said Genprex chair, president and CEO Rodney Varner in the press release. “Research indicates that the TUSC2 gene used in REQORSA may benefit many types of cancers and potentially the treatment of other diseases. We are exploring opportunities to treat other cancers in which TUSC2 is often deleted or inactivated, and we are evaluating TUSC2 basic biology to better understand how to use our REQORSA treatment. Finally, we are also exploring the use of another tumor suppressor gene, NPRL2, in cancer treatment using our Oncoprex(R) Nanoparticle Delivery System.”
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