NetworkNewsBreaks – CNS Pharmaceuticals Inc. (NA
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Posted On: 12/18/2023 4:34:24 PM
NetworkNewsBreaks – CNS Pharmaceuticals Inc. (NASDAQ: CNSP) Announces DSMB Recommendation to Continue Pivotal GBM Study without Modification
CNS Pharmaceuticals (NASDAQ: CNSP), a biopharmaceutical company specializing in the development of novel treatments for primary and metastatic cancers in the brain and central nervous system, announced a recommendation from the independent Data Safety Monitoring Board (“DSMB”) regarding Berubicin, the company’s investigational agent. According to the announcement, the DSMB recommends that CNS Pharmaceuticals’ ongoing global, potentially pivotal trial of Berubicin for the treatment of glioblastoma multiforme (“GBM”) continue without modification. The company also noted that it anticipated enrollment for the trial to be complete in the first quarter of 2024. The Berubicin study is a multicenter, open-label, randomized controlled study evaluating adult patients with recurrent GBM (WHO Grade IV) where standard first-line therapy has failed, compared to Lomustine. Berubicin is an anthracycline, which is a class of anticancer agents among the most powerful chemotherapy drugs and that are effective against more types of cancer than any other class of chemotherapeutic agents. “Having successfully reached this milestone, we believe that this recommendation reflects Berubicin’s acceptable efficacy and safety profile, as defined in the trial protocol, as of the interim analysis,” said CNS Pharmaceuticals CEO John Climaco in the press release. “Building on the foundation of strong enrollment laid by our team, our investigators and their patients, the independent findings of the DSMB add to the phase 1 trial data, where 44% of treated patients received a clinical benefit of stable disease or better. Finding an effective treatment for GBM remains one of the great challenges in oncology, and more meaningful options for the many patients who fail first-line therapy are still desperately needed after decades of research. With this recommendation to continue the study, our long-held belief that Berubicin will ultimately address the unmet clinical need of GBM patients now moves closer to becoming reality.”
Please see full terms of use and disclaimers on the NetworkNewsWire website applicable to all content provided by NNW, wherever published or re-published: http://NNW.fm/Disclaimer
CNS Pharmaceuticals (NASDAQ: CNSP), a biopharmaceutical company specializing in the development of novel treatments for primary and metastatic cancers in the brain and central nervous system, announced a recommendation from the independent Data Safety Monitoring Board (“DSMB”) regarding Berubicin, the company’s investigational agent. According to the announcement, the DSMB recommends that CNS Pharmaceuticals’ ongoing global, potentially pivotal trial of Berubicin for the treatment of glioblastoma multiforme (“GBM”) continue without modification. The company also noted that it anticipated enrollment for the trial to be complete in the first quarter of 2024. The Berubicin study is a multicenter, open-label, randomized controlled study evaluating adult patients with recurrent GBM (WHO Grade IV) where standard first-line therapy has failed, compared to Lomustine. Berubicin is an anthracycline, which is a class of anticancer agents among the most powerful chemotherapy drugs and that are effective against more types of cancer than any other class of chemotherapeutic agents. “Having successfully reached this milestone, we believe that this recommendation reflects Berubicin’s acceptable efficacy and safety profile, as defined in the trial protocol, as of the interim analysis,” said CNS Pharmaceuticals CEO John Climaco in the press release. “Building on the foundation of strong enrollment laid by our team, our investigators and their patients, the independent findings of the DSMB add to the phase 1 trial data, where 44% of treated patients received a clinical benefit of stable disease or better. Finding an effective treatment for GBM remains one of the great challenges in oncology, and more meaningful options for the many patients who fail first-line therapy are still desperately needed after decades of research. With this recommendation to continue the study, our long-held belief that Berubicin will ultimately address the unmet clinical need of GBM patients now moves closer to becoming reality.”
Please see full terms of use and disclaimers on the NetworkNewsWire website applicable to all content provided by NNW, wherever published or re-published: http://NNW.fm/Disclaimer
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