mRNA has become an emerging class of gene therapy

mRNA has become an emerging class of gene therapy because of its negligible cytotoxicity and immunogenicity. So, there is an increasing demand for efficient and robust production of mRNA molecules in both pharmaceutics and research field. In vitro transcription (IVT) is an elegant way to obtain highly pure and uniform mRNA oligonucleotides of lengths ranging from about 15 to several thousand nucleotides. It is transcribed from a double-stranded DNA template by RNA polymerase (T7, T3 or SP6 RNA polymerase). Creative Biolabs is a leading service provider in custom mRNA IVT synthesis for basic research and clinical applications. We provide best-fit Insert-tag-herein vitro transcription vectors that are simple and efficient systems for RNA synthesis, applicable for a variety of research purposes.