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Humans breeding with now-extinct species may be cause of depression, claims study
Story by Elin Johnson
Ancient humans mating with a now-extinct subspecies from Asia could be the reason we suffer with depression, a new study claims.
Researchers discovered a gene variant that can be traced back to humans hooking up with Denisovans.
(Researchers are also looking at a sub-group of Denisovans, the Denseovans; believed to have been much slower on the uptake and inclined toward violence, superstition and denial of tribal election results.)
In the study led by a team at Barcelona's Pompeu Fabra University, it is suggested that those with the gene variant today also tend to have lower levels of zinc in the body.
The nutrient zinc can be connected to mood and happiness.
The gene, SLC30A9, is one of the most widespread Denisovan genes discovered to date. Advancements in genomic sequencing made this discovery possible.
Three people in sepia tones holding tools
© ImagesbyTrista Getty
The SLC30A9 gene variant was discovered in Asia and then spread to European and North American populations - and may have once aided in Denisovans dealing with the cold climate of their region.
Researchers found the gene variant can cause a new zinc balance within a cell. This can affect metabolism.
Zinc is also involved in the nervous system and can affect mental equilibrium and health.
The variant found in this zinc transporter is affiliated with a predisposition to some psychiatric diseases including schizophrenia, hyperactivity disorder, autism spectrum disorder, bipolar disorder, anorexia nervosa and depression.
drawing of caveman using tool under blue sky
Researchers said people with Neanderthal heritage did not share this genetic mutation. The Denisovans are considered a sister species of the Neanderthal.
Introgression is the process where ancient human family trees interbred and therefore shared genes. It's happened numerous times.
Remains of the Denisovans have only been found in one location - a cave in Siberia - but DNA analysis shows the early humans were more widespread than that.
https://www.msn.com/en-us/health/medical/huma...&ei=62