Regulated by leronlimab - IL-1b (via caspase-1
Post# of 148110
IL-1b (via caspase-1 downreg)[-]
Quote:
When researchers artificially reduced the number of T regulatory (Treg) cells – known to help keep the immune system in check – some of the same effects were observed, opening a possible route that future treatments could take.
"Both menthol exposure and Treg cell blockade caused a decrease in IL-1β, a protein that could be behind the cognitive decline observed in these models," said neuroscientist Ana Garcia-Osta, from CIMA, at the time.
https://www.sciencealert.com/mouse-study-reve...alzheimers
Leronlimab also causes a significant reduction in Tregs. p value = .0123
Quote:
Percent of total immune cells in long-term Leronlimab treatment in humans