https://neurosciencenews.com/ferroptosis-iron-alzh
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Posted On: 09/05/2023 7:50:12 PM
https://neurosciencenews.com/ferroptosis-iron...ers-23880/
Excerpt: "Adeniyi subsequently developed a novel immunofluorescence technique to determine that iron toxicity was causing microglial degeneration in the brain. This was likely a result of the fact that the fragments of myelin are themselves rich in iron, Back said.
In effect, the immune cells were dying in the line of duty.
“Everyone knows that microglia are activated to mediate inflammation ,” Back said. “But no one knew that they were dying in such large numbers. It’s just amazing that we missed this until now.”
The study finds that the cascading effect of degenerating microglia appears to be a mechanism in advancing cognitive decline in Alzheimer’s disease and vascular dementia, Back said. He expects pharmaceutical companies will use this new finding to develop compounds focused on reducing microglial degeneration in the brain."
I see "inflammation" I think LL.
Excerpt: "Adeniyi subsequently developed a novel immunofluorescence technique to determine that iron toxicity was causing microglial degeneration in the brain. This was likely a result of the fact that the fragments of myelin are themselves rich in iron, Back said.
In effect, the immune cells were dying in the line of duty.
“Everyone knows that microglia are activated to mediate inflammation ,” Back said. “But no one knew that they were dying in such large numbers. It’s just amazing that we missed this until now.”
The study finds that the cascading effect of degenerating microglia appears to be a mechanism in advancing cognitive decline in Alzheimer’s disease and vascular dementia, Back said. He expects pharmaceutical companies will use this new finding to develop compounds focused on reducing microglial degeneration in the brain."
I see "inflammation" I think LL.
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