NetworkNewsBreaks – BiondVax Pharmaceuticals Ltd
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BiondVax (NASDAQ: BVXV), a biotechnology company focused on developing, manufacturing and commercializing innovative immunotherapeutic products primarily for the treatment of infectious and autoimmune diseases, was featured in the latest episode of the Bell2Bell Podcast. The podcast is part of IBN’s sustained effort to provide specialized content distribution via widespread syndication channels. BiondVax CEO Amir Reichman joined the program to discuss the company’s recent achievements. “At the end of 2022, we did a round of financing and raised about $8 million. We also started the negotiations to in-license the next antibody from the Max Planck Institute – namely the antibody for targeting interleukin-17 (‘IL-17’) for the treatment of psoriasis. We have now in-licensed the IL-17 nanobody. This is a highly promising drug,” Reichman said. “If we look at the market, psoriatic patients today have several options for treatment.
For example, plaque psoriasis patients have creams and other topical drugs, biologics and oral drugs… The topicals are not highly sophisticated drugs to say the least, and they come with a considerable profile of side effects. When a person needs to take steroids once in a while for an infection, they can tolerate it, but when you need to take steroids for an autoimmune disease with chronic inflammation, you create tolerance and deal with potential side effects… The biologics are highly potent, but they are restricted to moderate and severe cases of psoriasis; this accounts for only 15% of patients with psoriasis. The 85% that are left have to choose between drugs based on 1960s and 1970s technology. There hasn’t been much breakthrough in recent years to serve these patients… The total [annual] sales of anti-interleukin-17 monoclonal antibodies are about $7.5 billion. If you take all of the other psoriasis biologics, the market is about $10 billion per year, targeting only severe cases. What we want to do is generate an axis for a highly potent, highly specific drug that’s safe to use for mild-to-moderate psoriasis cases. This is where our nanobodies are the best fit… We can inject it in an affordable way directly to the lesion… to provide relief and alleviate inflammation. Then, the next treatment will come only with the next flareup, six months or a year later.”
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