NetworkNewsBreaks – Genprex Inc. (NASDAQ: GNPX)
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Genprex (NASDAQ: GNPX), a clinical-stage gene therapy company focused on developing life-changing treatments for patients with cancer and diabetes, recently announced that its research collaborators presented positive preclinical data for the NRPL2 tumor suppressor gene. “The studies used Genprex’s non-viral ONCOPREX(R) Nanoparticle Delivery System in KRAS/STK11 mutant anti-PD1 resistant metastatic human non-small cell lung cancer (‘NSCLC’) humanized mouse models. Genprex’s ONCOPREX(R) Nanoparticle Delivery System is a novel non-vital approach utilizing lipid nanoparticles to deliver tumor suppressor genes that have been deleted during the course of cancer development. The platform allows for intravenous delivery of various tumor suppressor genes, and potentially other genes, to achieve a therapeutic effect without the risk of toxicity often associated with viral delivery systems,” a recent article reads. “The preclinical data also provides further evidence that the ONCOPREX(R) Nanoparticle Delivery System has the ability to be successful using genes other than the TUSC2 gene that we are already using in clinical trials with REQORSA(R),” Rodney Varner, president and CEO of Genprex, is quoted as saying. “These compelling outcomes give us further confidence in the potentially broad-based applications of our non-vital delivery system, which may provide a multitude of potential pipeline opportunities in the future.”
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