This article verifies that CCR5 plays a crucial ro
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Posted On: 05/12/2023 10:26:31 AM
This article verifies that CCR5 plays a crucial role in increasing inflammatory macrophages to fight the bacteria. It looks like Leronlimab would take care of the immune system causing inflammation and, with an administered strong antibiotic, would be a very productive treatment for Sepsis.
"Furthermore, CCR5 plays an important role for the migration of the inflammatory monocytes to infection focus during sepsis. CCR5-expressing inflammatory monocytes migrate from the bone marrow to the circulation and then into the site of infection, where they phagocytize and kill the bacteria. Consequently, CCR5 mice showed increased systemic inflammatory response and mortality compared to wild-type mice."
https://pubmed.ncbi.nlm.nih.gov/30724784/#:~:...20bacteria.
"Furthermore, CCR5 plays an important role for the migration of the inflammatory monocytes to infection focus during sepsis. CCR5-expressing inflammatory monocytes migrate from the bone marrow to the circulation and then into the site of infection, where they phagocytize and kill the bacteria. Consequently, CCR5 mice showed increased systemic inflammatory response and mortality compared to wild-type mice."
https://pubmed.ncbi.nlm.nih.gov/30724784/#:~:...20bacteria.
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