"Tumor cells can “hijack” chemokine networks t
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Posted On: 05/06/2023 9:42:49 AM
"Tumor cells can “hijack” chemokine networks to support tumor progression. In this context, the C-C chemokine ligand 5/C-C chemokine receptor type 5 ( CCL5/CCR5) axis is gaining increasing attention , since abnormal expression and activity of CCL5 and its receptor CCR5 have been found in hematological malignancies and solid tumor. Numerous preclinical in vitro and in vivo studies have shown a key role of the CCL5/CCR5 axis in cancer, and thus provided the rationale for clinical trials using the repurposed drug maraviroc , a CCR5 antagonist used to treat HIV/AIDS. This review summarizes current knowledge on the role of the CCL5/CCR5 axis in cancer. "
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407580/
This molecule is inevitably going to wend its way on to the front pages of our daily newspapers and on to the front ranks of our public consciousness. Just as it is now making its way through the scientific community/literature.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407580/
This molecule is inevitably going to wend its way on to the front pages of our daily newspapers and on to the front ranks of our public consciousness. Just as it is now making its way through the scientific community/literature.
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