NetworkNewsBreaks – Aditxt Inc. (NASDAQ: ADTX) S
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Aditxt (NASDAQ: ADTX), a global innovation company focused on therapeutics and technologies that monitor and modulate the immune system, and its subsidiary Adimune(TM) Inc. announced a clinical trial agreement with Mayo Clinic. The clinical trial, which is designed to advance clinical studies targeting autoimmune diseases of the central nervous system (“CNS”), is expected to begin this year with an estimated 10 to 15 patients, some of whom may also suffer from type-1 diabetes; the initial focus of the study will be on the autoimmune disease Stiff Person Syndrome (“SPS”). According to the announcement, Adimune, which was created to lead Aditxt’s immune modulation therapeutic programs, has almost completed its preclinical package for the immunotherapy clinical study drug candidate ADI-100. The company noted that it has been working to launch ADI(TM)-100, its first immune modulation product candidate, for more than a year; the company has been targeting clinical trials to demonstrate its safety and indications of efficacy. “We are extremely pleased about having the opportunity to work with Mayo Clinic on trying to restore immune tolerance in patients suffering from devastating progressive autoimmune central nervous system disorders,” said Adimune co-CEO Dr. Joachim Friedrich Kapp in the press release. “The collaboration will include both preclinical and clinical studies and builds on Adimune’s current efforts to advance the full preclinical and clinical programs of ADI-100. We believe that the preclinical studies will help us to expand on the understanding of the technology, specifically the mechanism of action which induces antigen-specific immune tolerance without impairing the responsiveness of the immune system to fight infections and cancers.”
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