NetworkNewsBreaks – BiondVax Pharmaceuticals Ltd
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BiondVax Pharmaceuticals (NASDAQ: BVXV), a biotech company focused on developing, manufacturing and commercializing innovative immunotherapeutic products primarily for the treatment of infectious and autoimmune diseases, published its full-year financial results for the year ended December 31, 2022; the report also included key business updates. Highlights of the report include the signing of definitive agreements with the Max Planck Society (“MPG”) and the University Medical Center Göttingen, Germany (“UMG”) designed to enable BiondVax to build a pipeline of “bio-better” nanosized VHH antibodies (NanoAbs); notice that the unique physicochemical characteristics of NanoAbs being generated by BiondVax’s scientific partners show several competitive attributes, including greater binding affinity, neutralization at lower drug concentrations, stability at high temperatures, and convenient routes of administration and formulation advantages; and an option for an exclusive worldwide license agreement at pre-agreed financial terms for additional NanoAbs discovered and characterized under the BiondVax-MPG-UMG agreement.
In addition, the company is looking at starting a phase 1/2a clinical trial while continuing to monitor the ongoing evolution of the COVID-19 virus and variants of concern (“VoCs”). “BiondVax’s recent achievements leave me very optimistic about BiondVax’s growth potential and ability to deliver value to our stakeholders,” said BiondVax CEO Amir Reichman in the press release. “This past winter we published exciting data from the proof-of-concept in vivo trial of an inhaled NanoAb therapy. Looking forward, I’m excited to exercise our option to obtain an exclusive license at pre-agreed financial terms to anti-IL-17 NanoAbs targeting safe, effective and convenient treatment of psoriatic lesions; scale up in-house NanoAb manufacturing; and conduct an in vitro proof-of-concept study and potentially also a preclinical trial of the IL-17 NanoAb as a therapy for psoriasis. The BiondVax team, in collaboration with our scientific partners from MPI-NAT and UMG, has worked exceedingly hard to develop best in class capabilities in NanoAb technology-based drug development.”
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