NetworkNewsBreaks – Cybin Inc. (NEO: CYBN) (NYSE
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Posted On: 02/28/2023 3:36:21 PM
NetworkNewsBreaks – Cybin Inc. (NEO: CYBN) (NYSE American: CYBN) Releases Progress Updates on Two Clinical Development Programs
Cybin (NEO: CYBN) (NYSE American: CYBN), a biopharmaceutical company focused on progressing Psychedelics to Therapeutics(TM), is reporting on its two lead clinical development programs: CYB003, a proprietary deuterated psilocybin analog for the potential treatment of major depressive disorder (“MDD”), and CYB004, a proprietary deuterated N,N-dimethyltryptamine molecule being developed for the potential treatment of generalized anxiety disorder (“GAD”). According to the announcement, interim data from the CYB003 phase 1/2a study exhibited rapid and short-acting effects; strong psychedelic effects at low doses; and a positive safety and tolerability profile. The company anticipates having top-line efficacy data by late Q3 2023. In addition, initial findings from CYBN’s phase 1 CYB004-E study suggest that IV DMT is tolerated well, and the study design is being expanded to accelerate first-in-human dosing of CYB004. “It is incredibly gratifying that our findings from the interim readout of the CYB003 Phase 1/2a clinical trial align with the results observed in preclinical studies,” said Cybin CEO Doug Drysdale in the press release. “Robust psychedelic effects were observed at low doses, absorption was rapid with low variability, and effects were short lasting – all desired outcomes. These findings give us confidence in the potential efficacy of the underlying active agent, which may ultimately reduce symptoms of depression after just one or two doses. This would be a remarkable improvement over chronic treatments that are available today. . . . Our CYB004 program has made significant progress marked by confirmatory results from part A of the phase 1 CYB004-E trial and the acceleration of first-in-human dosing of CYB004. Recent protocol amendments will allow us to further evaluate CYB004 and demonstrate the advantages of deuteration on PK and PD parameters. We see the potential for short duration treatments, which could truly transform the treatment paradigm and outcomes for patients.”
Please see full disclaimers on the NetworkNewsWire website applicable to all content provided by NNW, wherever published or re-published: http://NNW.fm/Disclaimer
Cybin (NEO: CYBN) (NYSE American: CYBN), a biopharmaceutical company focused on progressing Psychedelics to Therapeutics(TM), is reporting on its two lead clinical development programs: CYB003, a proprietary deuterated psilocybin analog for the potential treatment of major depressive disorder (“MDD”), and CYB004, a proprietary deuterated N,N-dimethyltryptamine molecule being developed for the potential treatment of generalized anxiety disorder (“GAD”). According to the announcement, interim data from the CYB003 phase 1/2a study exhibited rapid and short-acting effects; strong psychedelic effects at low doses; and a positive safety and tolerability profile. The company anticipates having top-line efficacy data by late Q3 2023. In addition, initial findings from CYBN’s phase 1 CYB004-E study suggest that IV DMT is tolerated well, and the study design is being expanded to accelerate first-in-human dosing of CYB004. “It is incredibly gratifying that our findings from the interim readout of the CYB003 Phase 1/2a clinical trial align with the results observed in preclinical studies,” said Cybin CEO Doug Drysdale in the press release. “Robust psychedelic effects were observed at low doses, absorption was rapid with low variability, and effects were short lasting – all desired outcomes. These findings give us confidence in the potential efficacy of the underlying active agent, which may ultimately reduce symptoms of depression after just one or two doses. This would be a remarkable improvement over chronic treatments that are available today. . . . Our CYB004 program has made significant progress marked by confirmatory results from part A of the phase 1 CYB004-E trial and the acceleration of first-in-human dosing of CYB004. Recent protocol amendments will allow us to further evaluate CYB004 and demonstrate the advantages of deuteration on PK and PD parameters. We see the potential for short duration treatments, which could truly transform the treatment paradigm and outcomes for patients.”
Please see full disclaimers on the NetworkNewsWire website applicable to all content provided by NNW, wherever published or re-published: http://NNW.fm/Disclaimer
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