“-Leronlimab appears to ultimately "neutralize"
Post# of 148192
There are no neutralizing antibodies to Covid. Or any other coronavirus or retrovirus such as SARS or HIV. They’re only blocking antibodies.
Here is the difference between blocking and neutralizing antibodies.
“What Is The Difference Between Blocking And Neutralizing Antibodies?
A blocking antibody binds its target and directly interferes with its function, such as blocking cell adhesion or receptor-ligand binding. A neutralizing antibody binds its target and negates its downstream cellular effects, such as cell proliferation or chemotaxis.”
https://www.rndsystems.com/products/rnd-syste...antibodies
Basically, the Covid vaccine antibodies block disease progression but do not neutralize the virus.
Why Leronlimab is awesome, IMO, is that we rebalance the hereditary immune response well upstream of any viral infection.
We, nor any other antibody so far, neutralize coronaviruses. Some vaccines block disease by training the immune response to activate against a virus to block its bad downstream effects.
What the beauty of Leronlimab is, is that we are not the paddle, nor the canoe. We are the river.
Okay the immune system’s chemotaxis is the river, but we are the calm after the flood. In my opinion, we are the reason the flood never happens in the first place.
Immunologically, we are upstream of all of it. So when you say this….
“--Leronlimab appears to ultimately "neutralize" ALL variants of Covid through its unique mechanism of action.”…
You’re quite right about Leronlimab’s unique mechanism of helping modulate the immune response of ALL variants of Covid, however Leronlimab does not appear to ultimately neutralize anything, including Sars-CoV-2.