I always forget we don’t just inhibit the bad th
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Posted On: 01/26/2023 12:52:39 PM
I always forget we don’t just inhibit the bad things CCR5 can do but we are an immune modulator. I guess I forgot it’s not as simple as say, just the one example of binding to the receptor and blocking the migration of say cancer cells that expressed CCR5.
There is a lot more to it. Once CCR5 works properly it does a lot more. This is why restoring the immune system is so important in this area and this is what Leronlimab does.
"However, recently it has been reported that CCR5 on T cells and neutrophils acts as a decoy receptor for CCL3 and CCL5 to assist in resolution of inflammation."
Kinda interesting. Acts as a decoy. Your theory seems to be playing out in this article.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826270/
There is a lot more to it. Once CCR5 works properly it does a lot more. This is why restoring the immune system is so important in this area and this is what Leronlimab does.
"However, recently it has been reported that CCR5 on T cells and neutrophils acts as a decoy receptor for CCL3 and CCL5 to assist in resolution of inflammation."
Kinda interesting. Acts as a decoy. Your theory seems to be playing out in this article.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826270/
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