I was looking for the date of that article. It’s
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Posted On: 01/25/2023 9:47:15 PM
I was looking for the date of that article. It’s a general overview of chemokines and doesn’t mention LL. But the CCL5/CCR5 axis does get a mention, das well as the downstream benefits of immune modulation and anti inflammation.
“Different chemokine/chemokine receptors represent different immune responses types:
CCR1, CCR5, and CXCR3 are a feature of Th-1 immune response, and CCR3, CCR4, and CCR10 are the feature of Th-2 immune response [1]. In addition, CCR4 and CCR6 are highly expressed in Th17 cells while CCR6 and CXCR3 are highly expressed in Th17.1 cells [1], [67]. In humans and mice, chemokine receptors have different expression levels in memory T cells and effector cell subsets, providing specificity for cell trafficking in both homeostasis and inflammation.”
From the link I sent.
“Different chemokine/chemokine receptors represent different immune responses types:
CCR1, CCR5, and CXCR3 are a feature of Th-1 immune response, and CCR3, CCR4, and CCR10 are the feature of Th-2 immune response [1]. In addition, CCR4 and CCR6 are highly expressed in Th17 cells while CCR6 and CXCR3 are highly expressed in Th17.1 cells [1], [67]. In humans and mice, chemokine receptors have different expression levels in memory T cells and effector cell subsets, providing specificity for cell trafficking in both homeostasis and inflammation.”
From the link I sent.
(1)
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