WOW Very interesting who the new Independent Direc
Post# of 268
Dr.Sci Sanja Pekovic
Independent Director
Cellular and Molecular Basis of Neuroinflammation: Potential Targets for Translational Medicine and Therapy, Project leader: The research focus of this project is to highlight some cellular and molecular mechanisms which underlie neuroinflammation and to identify potential target molecules and signaling pathways. Our aim is to find adequate therapeutic approaches for the sanitation of neuroinflammation and the promotion of regeneration after central nervous system (CNS) damage. The efficacy of several therapeutic approaches (purine nucleoside analogs: Ribavirin and Tiazofurin, hyperbaric oxygenation, B vitamins - B1, B2, B3, B6, B12) in suppression of detrimental and enhancement of beneficial inflammatory mechanisms is tested. Considering the pivotal role of extracellular purine nucleotides and nucleosides in the control of neurodegenerative processes and inflammatory responses a particular focus is put on the regulation of their metabolism and the role of ectonucleotidases. In different animal models (brain injury, multiple sclerosis: experimental autoimmune encephalomyelitis, ischemia) behavioral, cellular, and molecular approaches (enzymatic assays, microdialysis combined with HPLC and bioluminescent detection, RT-PCR, immunoblot, and immunohistochemistry, ELISA, confocal microscopy and whole cell patch clamp) are used. Besides in vivo, neuroinflammatory processes are also studied in vitro in primary astrocytic and microglial cell cultures and glial cell lines.
Alexander Sentic
Independent Director
Alex Sentic s a businessperson who has been at the head of 9 different public companies. Alex Senticis versatile in financial services. Using his longtime experience in finance, sales, and his corporate development skills, backed by his large pool of business contacts, it did not take long for him to make a success in multiple corporate transactions, and past endeavors. Mr. Sentic is supported by multiple experienced CPAs that work in both Private and Public sectors. He also sustains multiple ongoing successful relationships with consultants with expertise in Public Companies, Equity Financing and Investment Banking. Mr. Senti has been a successful entrepreneur since a young age and has held multiple Executive Positions over the years. Mr. Sentic specializes in Interim Management coupled with his expertise of Corporate Development to uniquely assist both Private and Public trading companies