“When have we ever seen LL have a negative resul

“When have we ever seen LL have a negative result on other cytokines?”

I didn’t say it had negative effects on other cytokines. After a little wine, I was questioning whether interaction within the immune system between possibly competing cytokines could have caused a ceiling on LL’s effectiveness.

“Wouldn't a negative affect on other cytokines result in Adverse Events?”

IMO, not necessarily. An undesirable interaction of competing cytokines ‘could’ cause a Serious Adverse Event, but maybe it could just cause the immune system to try to do two different things at the same time and one wins out. Like tug-o-war. A little back and forth, but no SAE.

Cass, that’s why you do the studies. We shall see.

“It does what it does - bind to CCR5 - and a person's body and immune system has to take it from there.”

This part is particularly true, and pretty awesome. Binds a really special way in fact. It’s so far upstream in the bodies immune system that it stops a lot of things at the source. Instead of treating a bunch of symptoms way down stream in the immune system, we can potentially knock out a bunch before they get started by rebalancing or modulating the immune system.

It doesn’t mean LL is perfect. It still has to play in the same sand box with a whole bunch of other Cytokines. Each of those Cytokines has a purpose, a mission. And at the end there is give and take.