Nice writeup. In the news recently is another HIV
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Posted On: 07/27/2022 6:25:59 PM
Nice writeup. In the news recently is another HIV cure after stem cell therapy with CCR5 - donor, the City of Hope patient:
https://medicalxpress.com/news/2022-07-fourth...sight.html
The article talks about many thinking that CCR5 KO with gene therapy or gene editing would perhaps also do the trick, but another gene therapy to consider is Sacha's experiments to do AAV gene therapy to induce leronlimab production in T-cells in monkeys. Looking forward to the day that LRN is available as an HIV treatment and possibly some form of cure.
https://medicalxpress.com/news/2022-07-fourth...sight.html
Quote:
But he said that cases such as the City of Hope patient offered a potential roadmap towards a more broadly available cure, possibly using CRISPR gene-editing technology.
" I think that if you can get rid of HIV, and get rid of CCR5, the door by which HIV gets in, then you can cure someone ," Deeks said.
"It's theoretically possible—we're not there yet—to give someone a shot in the arm that will deliver an enzyme that will go into the cells and knock out CCR5, and knock out the virus.
"But that's science fiction for now."
The article talks about many thinking that CCR5 KO with gene therapy or gene editing would perhaps also do the trick, but another gene therapy to consider is Sacha's experiments to do AAV gene therapy to induce leronlimab production in T-cells in monkeys. Looking forward to the day that LRN is available as an HIV treatment and possibly some form of cure.
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