July < >, 2022 Dear Fellow Stockholder: You

July [ ], 2022

Dear Fellow Stockholder:

You are cordially invited to virtually attend a special meeting of stockholders of CytoDyn Inc. (the “Company”) to be held solely online via a live webcast at 9:30 a.m., Pacific Time, on Wednesday, August 31, 2022 at [ ]. To participate in the special meeting, you must be a stockholder of record as of the close of business on July 12, 2022.


The matters to be presented for action at the special meeting are a proposal to increase the total number of authorized shares of common stock from 1,000,000,000 to 1,350,000,000 shares, as further described in the enclosed proxy statement, and a proposal to approve the adjournment of the special meeting to solicit additional proxies if there are insufficient votes at this special meeting to approve the foregoing proposal.

We are excited about the future of our company. It is vitally important that your shares are represented and voted, whether or not you are able to attend the virtual meeting. We urge you to promptly vote and submit your proxy (1) via the Internet, (2) by phone, or (3) if you received your proxy materials by mail, by signing, dating, and returning the enclosed proxy card or voting instruction form in the envelope provided for your convenience.

Sincerely,

Antonio Migliarese

Chief Financial Officer and Interim President