Major spitballing before bed, but what if for some

Major spitballing before bed, but what if for some reason a more substantial receptor occupancy is somehow suboptimal in this disease? In muscarinic receptors, for instance, one receptor may be the dominant site for relaxing the smooth muscle of the bladder while another works as a negative feedback regulator and may need to be left alone for related bodily/muscarinic functions to run properly. Is it possible there’s any reason a stronger RO could cause some unintended consequence that ultimately lessens the effect in comparison to 350mg? #Spitballing #NewBootGoofin #TooDrunkToTasteThisChicken #Science