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  4. CytoDyn Inc (CYDY) Message Board

Interferon Gamma, Alpha would get expressed by the

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Post# of 154835
(Total Views: 422)
Posted On: 06/01/2022 6:21:55 PM
Posted By: ohm20
Re: MGK_2 #124078
Quote:
Interferon Gamma, Alpha would get expressed by the cells, if they awake from the dead. When LL binds to CCR5, the cells begin to awaken some how and then begin to express interferon alpha and gamma.



Is that how you think it works? You would be wrong. Chemokines exist in the body at low levels even if an inflammatory response doesn't exist or even when an immune response isn't needed. They also bind to CCR5 under those conditions. When leronlimab binds to CCR5 those chemokines remain unattached and spur the formation of new CCR5 receptors.

Quote:
So what you are suggesting is that with the 1st dose of LL, the binding of LL to CCR5 was enough to get the ball rolling.



You would also be wrong that I suggested that.

Quote:
LL binds to CCR5 and then the cell awakens from its trance, (likely CCL5 RANTES induced). That would mean CCL5 was displaced by LL by the way.



You also seem to be unaware that cells have life cycles and leronlimab can bind to new cells as they form and the older ones that are already bound with chemokines will die off.


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