Thanks ohm - fantastic point. Leronlimab gets
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Posted On: 05/27/2022 3:53:14 AM
Thanks ohm - fantastic point.
Leronlimab gets to the origin of the problem, the inflammatory state of the liver. Get rid of the inflammation and the fat melts away.
In NASH, the CCR5 receptors on the surface of the hepatocytes are all jam packed with CCL5 leading to the steatosis.
LL dislodges CCL5 from these CCR5 receptors and replaces them with itself, thereby putting a halt to the inflammatory state, (resulting in decreasing white fat), while inducing a healing response, (resulting in increasing brown fat).
Leronlimab gets to the origin of the problem, the inflammatory state of the liver. Get rid of the inflammation and the fat melts away.
In NASH, the CCR5 receptors on the surface of the hepatocytes are all jam packed with CCL5 leading to the steatosis.
LL dislodges CCL5 from these CCR5 receptors and replaces them with itself, thereby putting a halt to the inflammatory state, (resulting in decreasing white fat), while inducing a healing response, (resulting in increasing brown fat).
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