I feel strongly that CFS and probably other illnes

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I feel strongly that CFS and probably other illnesses that have similar symptoms, are largely, if not wholly, a result of microbiome imbalances, both in the small and large intestines, based on my many years of dealing with the illness.

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That explanation has been proposed by researchers in quite a few diseases. Personally I think the difference in gut bacteria is not a cause but a result. It's known that immune dysregulation, autoimmunity and the accompanying inflammation can compromise the microbiome so a result of not a cause. The surviving bacteria may be of the type to increase inflammation making for a vicious cycle.