The market will always dictate pricing value/etc...but the science will dictate the interest...Large Pharma needs the little guys to fuel their ascension in the ranks...Pharma BOD's are always looking for the next...bigger..better..best. That's what they have to contend with.... in their makeup...
Most of them spend more money on advertising than the development of drugs...they let the upstarts...do the heavy lifting and then they swoop in...it's the nature of things...in the industry.