Good question. They can absolutely tailor a dose based on

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Respert24 DJknows #114668
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Good question. They can absolutely tailor a dose based on what they learn through all these trials. That's why we've seen the introduction of IV in the hospitals, and the dose escalation to 700mg in certain disease states. There are also some reasons in dose choice that we might not be aware of. For instance, perhaps when making Leronlimab there are reasons outside of just efficacy and side effects when choosing a dose. Maybe they originally figured 300mg was the dose they'd roll with but then vial sizes don't come in 300mg sizes. Move up to 350mg and package two doses in one vial to keep things as efficient as possible. Or a variety of other reasons, that's just a random example.

When I sold Allegra years ago there were studies out showing that you could take 3x the highest 180mg dose without any sedation effect or increase in side effect profile. But you also didn't necessarily gain any additional efficacy. So they could have increased the standard dose but why bother. There are bound to be ranges where nothing much changes. Maybe 500 is just as good as 700. But then we're potentially wasting some product with each vial. Just make it 700mg. This is all just generalizing, of course. There could be more or less reasons specific to LL. But long story short, you're right they can do it, it just may not matter when both 350 and 700 are available.

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