Investors Hangout Stock Message Boards Logo
  • Mailbox
  • Favorites
  • Boards
    • The Hangout
    • NASDAQ
    • NYSE
    • OTC Markets
    • All Boards
  • Whats Hot!
    • Recent Activity
    • Most Viewed Boards
    • Most Viewed Posts
    • Most Posted
    • Most Followed
    • Top Boards
    • Newest Boards
    • Newest Members
  • Blog
    • Recent Blog Posts
    • Recently Updated
    • News
    • Stocks
    • Crypto
    • Investing
    • Business
    • Markets
    • Economy
    • Real Estate
    • Personal Finance
  • Market Movers
  • Interactive Charts
  • Login - Join Now FREE!
  1. Home ›
  2. Stock Message Boards ›
  3. Stock Boards ›
  4. CytoDyn Inc (CYDY) Message Board

Kabonk, Just when I think I've escaped the rabb

Message Board Public Reply | Private Reply | Keep | Replies (0)                   Post New Msg
Edit Msg () | Previous | Next


Post# of 153977
(Total Views: 584)
Posted On: 12/13/2021 7:05:33 PM
Posted By: CTMedic
Re: kabonk #112354
Kabonk,

Just when I think I've escaped the rabbit hole, you, Ohm and others drag me back in. There does not appear to be a bottom, as the more one looks the more one finds.

The CCL5/CCR5 axis as we know is ubiquitous in inflammatory processes. However, it is still incredibly illuminating to read the insights of researchers.

From a 2020 research article:

Functional roles of CCL5/RANTES in liver disease

https://www.sciencedirect.com/science/article...otnote-id2

Quote:
Inflammation, which is mediated by leukocyte trafficking and activation, plays a prominent role in the pathogenesis of acute and chronic liver injury. Chemokines are critical mediators involved in the migration of leukocytes into the diseased liver via binding to their G protein-coupled receptors. C–C motif ligand 5 (CCL5) belongs to the CC-chemokine family and is secreted by several hepatic cell populations including hepatocytes, macrophages, hepatic stellate cells, and endothelial cells upon activation. CCL5 regulates the recruitment and migration of T cells (via CCR5) and NK cells (via CCR1). Moreover, CCL5 activates and stimulates T cell proliferation and cytokine production, sequentially regulating inflammatory responses. Accumulating studies have identified crucial effects of CCL5 both in liver-disease patients and in experimental models, in which CCL5 is elevated and displays distinct effects according to pathological conditions. In this review, we discussed the crucial functions of CCL5 in liver diseases, including acute liver failure, hepatic ischemia-reperfusion injury, acute liver failure, acute and viral hepatitis, alcoholic liver disease, non-alcoholic fatty liver disease, fibrosis, and hepatocellular carcinoma. Continued understanding the roles of CCL5 in liver disease and their mechanisms of activation are indispensable for the development of effective clinical therapeutics.



957523054_CCL5Fibrosis.png


(9)
(0)




CytoDyn Inc (CYDY) Stock Research Links


  1.  
  2.  


  3.  
  4.  
  5.  






Investors Hangout

Home

Mailbox

Message Boards

Favorites

Whats Hot

Blog

Settings

Privacy Policy

Terms and Conditions

Disclaimer

Contact Us

Whats Hot

Recent Activity

Most Viewed Boards

Most Viewed Posts

Most Posted Boards

Most Followed

Top Boards

Newest Boards

Newest Members

Investors Hangout Message Boards

Welcome To Investors Hangout

Stock Message Boards

American Stock Exchange (AMEX)

NASDAQ Stock Exchange (NASDAQ)

New York Stock Exchange (NYSE)

Penny Stocks - (OTC)

User Boards

The Hangout

Private

Global Markets

Australian Securities Exchange (ASX)

Euronext Amsterdam (AMS)

Euronext Brussels (BRU)

Euronext Lisbon (LIS)

Euronext Paris (PAR)

Foreign Exchange (FOREX)

Hong Kong Stock Exchange (HKEX)

London Stock Exchange (LSE)

Milan Stock Exchange (MLSE)

New Zealand Exchange (NZX)

Singapore Stock Exchange (SGX)

Toronto Stock Exchange (TSX)

Contact Investors Hangout

Email Us

Follow Investors Hangout

Twitter

YouTube

Facebook

Market Data powered by QuoteMedia. Copyright © 2025. Data delayed 15 minutes unless otherwise indicated (view delay times for all exchanges).
Analyst Ratings & Earnings by Zacks. RT=Real-Time, EOD=End of Day, PD=Previous Day. Terms of Use.

© 2025 Copyright Investors Hangout, LLC All Rights Reserved.

Privacy Policy |Do Not Sell My Information | Terms & Conditions | Disclaimer | Help | Contact Us